Giuseppe Bianchi Selected Research

rostafuroxin

1/2021	Antihypertensive treatment guided by genetics: PEARL-HT, the randomized proof-of-concept trial comparing rostafuroxin with losartan.
11/2014	Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain.
1/2011	Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
11/2010	Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.
3/2006	Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension.
9/2005	The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications.
12/2002	PST 2238: a new antihypertensive compound that modulates renal Na-K pump function without diuretic activity in Milan hypertensive rats.

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Giuseppe Bianchi Research Topics

Disease

44	Hypertension (High Blood Pressure) 03/2016 - 02/2002
21	Essential Hypertension 01/2021 - 12/2002
8	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 01/2011
7	Neoplasms (Cancer) 03/2022 - 04/2014
6	Hypertrophy 09/2012 - 01/2004
5	Heart Failure 01/2022 - 03/2006
4	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2020
4	Infections 10/2021 - 01/2018
3	Pain (Aches) 09/2021 - 01/2009
2	Fibrosis (Cirrhosis) 01/2022 - 01/2004
2	Margins of Excision 01/2022 - 01/2011
2	Osteoarthritis 06/2021 - 08/2016
2	Proteinuria 11/2014 - 02/2010
2	Stroke (Strokes) 04/2006 - 01/2004
2	Myocardial Infarction 04/2006 - 01/2004
2	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 09/2005 - 01/2005
1	Ewing Sarcoma (Sarcoma, Ewing) 03/2022
1	Diabetic Cardiomyopathies 01/2022
1	Bone Diseases (Bone Disease) 01/2022
1	Discitis 09/2021
1	Pneumonia (Pneumonitis) 09/2021
1	Femoral Fractures (Femoral Fracture) 08/2021
1	Congenital Abnormalities (Deformity) 06/2021
1	Multiple Hereditary Exostoses (Hereditary Multiple Exostoses) 06/2021
1	Hip Osteoarthritis (Coxarthrosis) 06/2021
1	Giant Cell Tumors (Giant Cell Tumor) 09/2020
1	Solitary Fibrous Tumors 03/2020
1	Hypotension (Low Blood Pressure) 01/2020
1	Neurofibrosarcoma (MPNST) 01/2020
1	Chondrosarcoma 01/2020
1	Injection Site Reaction 01/2020
1	Myxoid Liposarcoma 06/2019
1	Synovial Sarcoma (Synovioma) 06/2019
1	Persistent Infection 01/2019
1	Disease Progression 11/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2013

Drug/Important Bio-Agent (IBA)

35	adducinIBA 11/2014 - 02/2002
20	Ouabain (G Strophanthin)IBA 11/2014 - 08/2004
20	SodiumIBA 07/2011 - 12/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2002
9	SaltsIBA 08/2011 - 05/2004
7	rostafuroxinIBA 01/2021 - 12/2002
7	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 12/2002
7	Adenosine Triphosphatases (ATPase)IBA 11/2014 - 11/2004
6	Pharmaceutical PreparationsIBA 01/2022 - 05/2003
6	AldosteroneIBA 09/2012 - 12/2002
6	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 12/2004 - 08/2002
5	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 12/2004 - 08/2002
4	IstaroximeIBA 01/2022 - 01/2007
4	CalciumIBA 08/2013 - 03/2002
4	DiureticsIBA 04/2006 - 12/2002
3	ReninIBA 07/2006 - 12/2002
3	PotassiumIBA 07/2006 - 10/2005
2	MineralsIBA 01/2022 - 09/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 09/2021 - 01/2019
2	Dihydrotachysterol (AT 10)IBA 05/2021 - 05/2018
2	Biological ProductsIBA 03/2020 - 11/2010
2	Therapeutic UsesIBA 11/2014 - 09/2006
2	SteroidsIBA 09/2012 - 04/2009
2	Calcium-Sensing ReceptorsIBA 07/2006 - 10/2002
2	Angiotensin IIIBA 12/2004 - 10/2004
2	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 03/2003 - 12/2002
1	EWS-FLI fusion proteinIBA 03/2022
1	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 01/2022
1	ElementsIBA 12/2021
1	3,5-tetrahydroaldosterone sulfate (THAS)IBA 06/2021
1	Losartan (Cozaar)FDA LinkGeneric 01/2021
1	Dacarbazine (DIC)FDA LinkGeneric 01/2020
1	Etoposide (VP 16)FDA LinkGeneric 01/2020
1	AnthracyclinesIBA 01/2020
1	Gemcitabine FDA Link 01/2020
1	Ifosfamide FDA LinkGeneric 01/2020
1	TrabectedinIBA 01/2020
1	Docetaxel (Taxotere)FDA Link 01/2020
1	GadoliniumIBA 10/2019
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/2019
1	Glucose (Dextrose)FDA LinkGeneric 06/2019
1	Dithiothreitol (Cleland's Reagent)IBA 01/2018
1	Narcotics (Narcotic Analgesics)IBA 12/2016
1	nephrinIBA 11/2014
1	Bleomycin (Blenoxane)FDA LinkGeneric 04/2014
1	phospholambanIBA 08/2013
1	AngiotensinsIBA 08/2013
1	CationsIBA 08/2013

Therapy/Procedure

12	Therapeutics 09/2021 - 03/2003
5	Radiotherapy 08/2021 - 01/2011
3	Drug Therapy (Chemotherapy) 01/2022 - 09/2021
3	Neoadjuvant Therapy 01/2022 - 01/2020
2	Arthrodesis 09/2020 - 09/2019
2	Prostheses and Implants (Prosthesis) 01/2019 - 01/2009
2	Knee Prosthesis 08/2016 - 01/2009
1	Aftercare (After-Treatment) 10/2021
1	Hip Replacement Arthroplasty (Total Hip Replacement) 06/2021
1	Metastasectomy 01/2020
1	Arthroplasty 01/2018
1	Reoperation 01/2018
1	Brachytherapy 06/2017
1	Adjuvant Radiotherapy 06/2017
1	Precision Medicine 03/2016
1	Electrodes (Electrode) 04/2014